Molecules (Jun 2010)

Alkaloids from Fissistigma latifolium (Dunal) Merr.

  • Asmah Alias,
  • Hazrina Hazni,
  • Faridahanim Mohd Jaafar,
  • Khalijah Awang,
  • Nor Hadiani Ismail

DOI
https://doi.org/10.3390/molecules15074583
Journal volume & issue
Vol. 15, no. 7
pp. 4583 – 4588

Abstract

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A phytochemical study of the bark of Fissistigma latifolium (Annonaceae) yielded a new aporphine alkaloid, (-)-N-methylguattescidine (1), and eight known alkaloids: liriodenine (2), oxoxylopine (3), (-)-asimilobine (4), dimethyltryptamine (5), (-)-remerine (6), (-)-anonaine (7), columbamine (8) and lysicamine (9). The compounds were isolated using various chromatographic methods and structural elucidation was accomplished by means of spectroscopic methods, notably 1D-NMR (1H, 13C, DEPT), 2D-NMR (COSY, HMQC, HMBC), UV, IR and MS.

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