Journal of Saudi Chemical Society (Jan 2024)
Unlocking nature's potential: Green synthesis of ZnO nanoparticles and their multifaceted applications – A concise overview
Abstract
In recent years, zinc oxide nanoparticles (ZNPs) have gained tremendous attention attributed to their unique properties. It is the most desirable group of nanostructures as far as both structure and properties are concerned. It is an adaptable material that has distinctive properties, such as high sensitivity, large specific area, non-toxicity, good compatibility, and a high isoelectric point, which favors it to be considered with a few exceptions. They are utilized in an expanding number of mechanical items, for example, elastic, paint, coating, cosmetics, supercapacitors, Lithium batteries, color-sensitized sun-powered cells, photocatalysis, biosensors, biomedical and characteristic applications. They have brought a promising potential up in biomedicine, especially in the fields of anticancer and antibacterial fields, which are locked in with their solid ability to trigger plenitude reactive oxygen species (ROS) creation, discharge zinc particles, and instigate cell apoptosis. ZNPs have also been successfully utilized to transport and load drugs to target locations as drug carriers, reducing undesirable toxicity and non-target effects and increasing the synergistic effects. In addition, ZNPs display outstanding light assets and this property has made them one of the chief bioimaging applicants Thus, this paper reviews the biological synthesis of ZNPs by the microbes, the mechanisms of the biological synthesis, parameters for the optimization process and their potential application as an antimicrobial agent and feed supplement in the animal industry as well as their toxicological hazards on animals. Here, we summarize the synthesis and recent advances of ZNPs in the biomedical fields, which will be helpful for facilitating their future research progress and focusing on biomedical fields.
