Качественная клиническая практика (Oct 2020)

Use of etiotropic and pathogenetic medicines for COVID-19 in patients with renal failure and/or on dialysis

  • V. M. Tsvetov,
  • I. N. Sychev,
  • D. A. Sychev

DOI
https://doi.org/10.37489/2588-0519-2020-S4-39-46
Journal volume & issue
Vol. 0, no. 4S
pp. 39 – 46

Abstract

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Impaired kidney function may influence pharmacokinetics of most of the drugs, including the ones used in COVID-19. In this publication, the most important pharmacokinetic parameters and dose adjustment approaches are provided, based on The Renal Drug Handbook и Sanford Guide. In the majority of cases, mild kidney function reduction does not necessitate dose adjustment. Each case should be considered individually, measuring benefits against risks.

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