Известия высших учебных заведений. Поволжский регион: Медицинские науки (Dec 2020)

STRATEGY FOR SELECTING ANTITROMBOTIC DRUGS FOR PATIENTS WITH ATRIAL FIBRILLATION AND SENILE ASTHENIA SYNDROME

  • L. F. Burmistrova,
  • F. K. Rakhmatullov,
  • A. E. Sheina,
  • A. Yu. Shorina,
  • M. E. Burmistrov

DOI
https://doi.org/10.21685/2072-3032-2020-4-1
Journal volume & issue
no. 4

Abstract

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Background. Heart rhythm disturbances are currently in the spotlight, as they constitute one of the key positions among cardiovascular diseases, which ultimately can lead to the development of cardiovascular catastrophes, disability and patient death. The detection of senile asthenia syndrome, especially in combination with atrial fibrillation in elderly and senile patients, is very important for the timely administration of drug therapy, including antithrombotic, which prevents the development of complications and other adverse outcomes in this category of patients. The purpose of this work is to study the timely appointment of antithrombotic therapy in order to prevent adverse outcomes in patients with atrial fibrillation in combination with senile asthenia syndrome. Materials and methods. The study was retrospective and included 150 patients hospitalized in the cardiology unit of G. A. Zakharyin Clinical Hospital No. 6 in 2017–2019. All patients underwent the following diagnostic methods: “Age is not a hindrance” questionnaire, CHA2DS2-VASc and HAS-BLED prediction scales, echocardiography. Results. According to a retrospective analysis of hospitalized patients with atrial fibrillation and senile asthenia syndrome by age groups, the following was revealed: after assessing the risk of thromboembolic complications in patients with atrial fibrillation according to the CHA2DS2-VAS scale, all hospitalized patients were prescribed anticoagulant therapy; 21.1 % of patients had already received anticoagulant therapy at the prehospital stage; the risk of bleeding, assessed according to the HASBLED scale, in 115 patients (76.7 %) ranged from 3 points or more. Conclusions. Thus, in the course of the study, it was found that senile asthenia syndrome is not a contraindication to the appointment of antiplatelet therapy in elderly patients with atrial fibrillation. This will increase life expectancy and improve the quality of life of the said patients.

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