Pathogens (Sep 2023)

Mucosal Relapse of Visceral Leishmaniasis in a Child with SARS-CoV-2 Infection

  • Claudia Colomba,
  • Giovanni Boncori,
  • Chiara Albano,
  • Valeria Garbo,
  • Sara Bagarello,
  • Anna Condemi,
  • Salvatore Giordano,
  • Antonio Cascio

DOI
https://doi.org/10.3390/pathogens12091127
Journal volume & issue
Vol. 12, no. 9
p. 1127

Abstract

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Leishmaniasis is a vector-borne disease caused by protozoan parasites of the genus Leishmania and is transmitted through the bite of infected female sandflies. In the Mediterranean region, visceral leishmaniasis is caused by Leishmania. infantum, and it is usually responsible for symptoms such as fever, pancytopenia and enlargement of the liver and spleen. Relapse is rare in immunocompetent patients as much as the mucous involvement. We present a rare case of mucosal relapse of visceral leishmaniasis in a child with SARS-CoV-2 infection and perform an extensive review of the literature about leishmaniasis relapses in children. Atypical mucosal involvement during Leishmaniasis relapse is an eventuality in pediatric patients. Clinical follow-up and periodic PCR tests must be considered essential for the early recognition and treatment of an eventual relapse.

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