Antimicrobial properties of metal piperidine dithiocarbamate complexes against Staphylococcus aureus and Candida albicans

Nathaniel Owusu Boadi; Mawuli Degbevi; Selina Ama Saah; Mercy Badu; Lawrence Sheringham Borquaye; Nii Korley Kortei

Scientific African (Jul 2021)

Antimicrobial properties of metal piperidine dithiocarbamate complexes against Staphylococcus aureus and Candida albicans

Nathaniel Owusu Boadi,
Mawuli Degbevi,
Selina Ama Saah,
Mercy Badu,
Lawrence Sheringham Borquaye,
Nii Korley Kortei

Affiliations

Nathaniel Owusu Boadi: Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Corresponding author.
Mawuli Degbevi: Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Selina Ama Saah: Department of Chemical Sciences, University of Energy and Natural Resources, Sunyani, Ghana
Mercy Badu: Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Lawrence Sheringham Borquaye: Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Central Laboratory, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Nii Korley Kortei: Department of Nutrition and Dietetics, School of Allied Health Sciences, University of Health and Allied Sciences, PMB 31 Ho, Ghana

Journal volume & issue: Vol. 12
p. e00846

Abstract

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In this study, a series of metal piperidine dithiocarbamate complexes (M = Zn, Cu, Co, Fe, Ni, Bi and Ag) were synthesized and characterized using microelemental, 1HNMR, mass spectrometry and FT-IR analyses. Antimicrobial properties of the complexes were tested against Staphylococcus aureus and Candida albicans in a 96-well plate, using the broth dilution assay. The antimicrobial activity of the complexes was in the order Zn>Co>Cu>Ag=Bi=Ni>Fe against Staphylococcus aureus and Co> Zn >Fe>Ag=Bi=Cu=Ni against Candida albicans. The results indicate that the complexes were effective against the microorganisms at high concentrations.

Published in Scientific African

ISSN: 2468-2276 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science
Website: https://www.journals.elsevier.com/scientific-african

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