Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation

Ishita Jain; Ian C. Berg; Ayusha Acharya; Maddie Blaauw; Nicholas Gosstola; Pablo Perez-Pinera; Gregory H. Underhill

doi:10.1038/s42003-022-03840-9

Communications Biology (Oct 2022)

Delineating cooperative effects of Notch and biomechanical signals on patterned liver differentiation

Ishita Jain,
Ian C. Berg,
Ayusha Acharya,
Maddie Blaauw,
Nicholas Gosstola,
Pablo Perez-Pinera,
Gregory H. Underhill

Affiliations

Ishita Jain: Department of Bioengineering, University of Illinois at Urbana Champaign
Ian C. Berg: Department of Bioengineering, University of Illinois at Urbana Champaign
Ayusha Acharya: Department of Bioengineering, University of Illinois at Urbana Champaign
Maddie Blaauw: Department of Bioengineering, University of Illinois at Urbana Champaign
Nicholas Gosstola: Department of Bioengineering, University of Illinois at Urbana Champaign
Pablo Perez-Pinera: Department of Bioengineering, University of Illinois at Urbana Champaign
Gregory H. Underhill: Department of Bioengineering, University of Illinois at Urbana Champaign

DOI: https://doi.org/10.1038/s42003-022-03840-9
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 16

Abstract

Read online

Integrating cellular microarrays, experimental and computational data for liver progenitor cell differentiation patterning, the interplay between Notch signaling and cellular mechanics is assessed.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal