Preliminary study of neuroimaging and psychophysiology in adults with ADHD

Ni Chun Hung; Shin-Hsien Lin; Mei Hung Chi; Po See Chen; I Hui Lee; Kao Chin Chen; Yen Kuang Yang

International Journal of Child Development and Mental Health (Jul 2014)

Preliminary study of neuroimaging and psychophysiology in adults with ADHD

Ni Chun Hung,
Shin-Hsien Lin,
Mei Hung Chi,
Po See Chen,
I Hui Lee,
Kao Chin Chen,
Yen Kuang Yang

Affiliations

Ni Chun Hung: Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan Department of Psychiatry, Chi-Mei Foundation Medical Center, Tainan, Taiwan
Shin-Hsien Lin: Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan.
Mei Hung Chi: Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Po See Chen: Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, NationalCheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan
I Hui Lee: Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan
Kao Chin Chen: Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan. Department of Psychiatry, National Cheng Kung University, Dou-Liou Branch, Yunlin, Taiwan.
Yen Kuang Yang: Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan

Journal volume & issue: Vol. 2, no. 2
pp. 23 – 35

Abstract

Read online

Attention Deficit Hyperactivity Disorder (ADHD) affects in both children and adults leading to poor executive functioning and quality of life. However, very little study focuses on neuroimaging and psychophysiology in the adults with ADHD. This preliminary study aimed to report neuroimaging and psychophysiology outcomes in the adults with ADHD. Participants in this study consisted of three groups: unaffected fathers of offspring with ADHD, adults with ADHD, and matched controls, were enrolled. A psychological battery was used in order to assess the participants’ cool cognitive function. Levels of dopaminergic activity were assessed by using the single positron emission computed tomography (SPECT) with [99mTc] TRODAT-1. In a pilot test for further study, the Iowa gambling test in a mock functional MRI was conducted. Molecular neuroimaging indicated the pivotal role of dopaminergicactivity altered a swellas functional brain imaging demonstrated difference between cool and hot executive functions. Using the Event-Related Potentials (ERP), the P300 amplitude of adults with ADHD was found to be lower than healthy group. In conclusions, Neuroimaging and psychophysiology outcome were effectively identified in adult with ADHD. Further study of neuroendocrinological factors might be related.

Published in International Journal of Child Development and Mental Health

ISSN: 2286-7481 (Print); 2586-887X (Online)
Publisher: Rajanagarindra Institute of Child Development
Country of publisher: Thailand
LCC subjects: Medicine: Other systems of medicine: Mental healing; Philosophy. Psychology. Religion: Psychology
Website: https://www.tci-thaijo.org/index.php/cdmh

About the journal

Abstract

Keywords