Tumor Suppression by p53: Is Apoptosis Important or Not?

Hestia Mellert; Joaquín M. Espinosa

doi:10.1016/j.celrep.2013.05.011

Cell Reports (May 2013)

Tumor Suppression by p53: Is Apoptosis Important or Not?

Hestia Mellert,
Joaquín M. Espinosa

Affiliations

Hestia Mellert: Howard Hughes Medical Institute and Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, CO 80309, USA
Joaquín M. Espinosa: Howard Hughes Medical Institute and Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, CO 80309, USA

DOI: https://doi.org/10.1016/j.celrep.2013.05.011
Journal volume & issue: Vol. 3, no. 5
pp. 1335 – 1336

Abstract

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The mechanisms by which p53 suppresses tumor growth remain ill defined. In this issue of Cell Reports, Timofeev et al. (2013) and Valente et al. (2013) reveal context-dependent contributions of p53-dependent apoptosis to its tumor-suppressive function.

Published in Cell Reports

ISSN: 2211-1247 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: http://www.cell.com/cell-reports/home

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