Kidney & Blood Pressure Research (Jun 2016)

Osteoporosis and Impaired Trabecular Bone Score in Hemodialysis Patients

  • Ludmila Brunerová,
  • Petra Ronová,
  • Jana Verešová,
  • Petra Beranová,
  • Jana Potoèková,
  • Petr Kasalický,
  • Ivan Rychlík

DOI
https://doi.org/10.1159/000443439
Journal volume & issue
Vol. 41, no. 3
pp. 345 – 354

Abstract

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Background/Aims: Small attention is paid to other types of bone diseases then chronic kidney disease-mineral and bone disorder in dialysis patients. The aim of our study was to assess the occurrence of osteoporosis and bone microarchitecture by trabecular bone score in this population. Methods: 59 patients (67.6 ± 13.1 years, 43 males) treated with hemodiafIltration underwent densitometry (Lunar Prodigy, TBS software 2.1.2) and laboratory assessment. Results: Osteoporosis was observed in 34% patients, high bone turnover was found in 80% of them, with SHPT (PTH > 300 ng/l) present in 69%. TBS was significantly decreased in 47.5% of the patients. TBS correlated with T- and Z-scores of the lumbar spine and proximal femur in the total population (P Conclusions: Osteoporosis was found in about 1/3 of patients treated with hemodiafiltration. Normal TBS was found in only 1/4 of the dialysis population. TBS correlated with densitometric parameters and was significantly different relative to T-scores.

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