Identification of potent SENP1 inhibitors that inactivate SENP1/JAK2/STAT signaling pathway and overcome platinum drug resistance in ovarian cancer

• Yi Zhang,
• Huiqiang Wei,
• Yuan Zhou,
• Zhuqing Li,
• Wenfeng Gou,
• Yunxiao Meng,
• Wei Zheng,
• Jing Li,
• Yiliang Li,
• Wenge Zhu

Affiliations

Yi Zhang

Department of Biochemistry and Molecular Medicine the George Washington University School of Medicine and Health Sciences Washington District of Columbia USA

Huiqiang Wei

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine Peking Union Medical College and Chinese Academy of Medical Sciences Tianjin China

Yuan Zhou

Department of Biochemistry and Molecular Medicine the George Washington University School of Medicine and Health Sciences Washington District of Columbia USA

Zhuqing Li

Department of Biochemistry and Molecular Medicine the George Washington University School of Medicine and Health Sciences Washington District of Columbia USA

Wenfeng Gou

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine Peking Union Medical College and Chinese Academy of Medical Sciences Tianjin China

Yunxiao Meng

Department of Biochemistry and Molecular Medicine the George Washington University School of Medicine and Health Sciences Washington District of Columbia USA

Wei Zheng

National Center for Advancing Translational Sciences National Institutes of Health Bethesda Maryland USA

Jing Li

Department of Biochemistry and Molecular Medicine the George Washington University School of Medicine and Health Sciences Washington District of Columbia USA

Yiliang Li

Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine Peking Union Medical College and Chinese Academy of Medical Sciences Tianjin China

Wenge Zhu

Department of Biochemistry and Molecular Medicine the George Washington University School of Medicine and Health Sciences Washington District of Columbia USA