Open-source curation of a pancreatic ductal adenocarcinoma gene expression analysis platform (pdacR) supports a two-subtype model

Luke A. Torre-Healy; Ryan R. Kawalerski; Ki Oh; Lucie Chrastecka; Xianlu L. Peng; Andrew J. Aguirre; Naim U. Rashid; Jen Jen Yeh; Richard A. Moffitt

doi:10.1038/s42003-023-04461-6

Communications Biology (Feb 2023)

Open-source curation of a pancreatic ductal adenocarcinoma gene expression analysis platform (pdacR) supports a two-subtype model

Luke A. Torre-Healy,
Ryan R. Kawalerski,
Ki Oh,
Lucie Chrastecka,
Xianlu L. Peng,
Andrew J. Aguirre,
Naim U. Rashid,
Jen Jen Yeh,
Richard A. Moffitt

Affiliations

Luke A. Torre-Healy: Department of Biomedical Informatics, Stony Brook Medicine
Ryan R. Kawalerski: Department of Biomedical Informatics, Stony Brook Medicine
Ki Oh: Department of Biomedical Informatics, Stony Brook Medicine
Lucie Chrastecka: Department of Pharmacological Sciences, Stony Brook Medicine
Xianlu L. Peng: Department of Pharmacology, University of North Carolina
Andrew J. Aguirre: Department of Medical Oncology, Dana-Farber Cancer Institute
Naim U. Rashid: Lineberger Comprehensive Cancer Center, University of North Carolina
Jen Jen Yeh: Department of Pharmacology, University of North Carolina
Richard A. Moffitt: Department of Biomedical Informatics, Stony Brook Medicine

DOI: https://doi.org/10.1038/s42003-023-04461-6
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 10

Abstract

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pdacR is an open-source R package and web-based platform that enables community exploration of pancreatic ductal adenocarcinoma (PDAC) gene expression datasets. pdacR is used to interrogate the specificities of popular PDAC molecular subtypes.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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