Surgical & Cosmetic Dermatology (Dec 2024)

Recurrent extramammary Paget’s disease successfully treated with peripheric Mohs micrographic surgery associated with rapid immunohistochemistry

  • José Antonio Jabur,
  • Selma Schuartz Cernea,
  • Bianca Spina Papaleo,
  • Rute Facchini Lellis

DOI
https://doi.org/10.5935/scd1984-8773.2024160280
Journal volume & issue
Vol. 16

Abstract

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Extramammary Paget's disease is a slow-progressing, cutaneous adenocarcinoma of the apocrine glands with an uncertain etiology. The standard treatment is surgical removal of the tumor. However, the usual surgical methods - wide local excision and Mohs micrographic surgery - pose challenges and high recurrence rates. Often, these are extensive lesions with poorly defined boundaries located in critical anatomical regions. Additionally, they exhibit unpredictable subclinical intraepithelial spread. We present a case of a recurrent extramammary Paget's disease successfully treated with peripheric Mohs micrographic surgery associated with rapid immunohistochemistry for CK8/18.

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