Hearts (Mar 2024)

Complications in Acute Myocardial Infarction: Navigating Challenges in Diagnosis and Management

  • Errol Moras,
  • Shreyas Yakkali,
  • Kruti D. Gandhi,
  • Hafeez Ul Hassan Virk,
  • Mahboob Alam,
  • Syed Zaid,
  • Nitin Barman,
  • Hani Jneid,
  • Saraschandra Vallabhajosyula,
  • Samin K. Sharma,
  • Chayakrit Krittanawong

DOI
https://doi.org/10.3390/hearts5010009
Journal volume & issue
Vol. 5, no. 1
pp. 122 – 141

Abstract

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In recent decades, significant advancements in pharmacological, catheter-based, and surgical reperfusion technologies have markedly improved outcomes for individuals undergoing acute myocardial infarction. Despite these remarkable progressions, a segment of patients, particularly those with extensive infarctions or delays in revascularization, remains vulnerable to the onset of mechanical complications associated with myocardial infarction. These complications, spanning mechanical, electrical, ischemic, inflammatory, and thromboembolic events, pose substantial risks of morbidity, mortality, and increased utilization of hospital resources. The management of patients experiencing these complications is intricate, necessitating collaborative efforts among various specialties. Timely identification, accurate diagnosis, hemodynamic stabilization, and decision-making support are crucial for guiding patients and their families in choosing between definitive treatments or palliative care. This review underscores the critical importance of promptly identifying and initiating therapy to reduce prolonged periods of cardiogenic shock and the potential for fatality. By presenting key clinical and diagnostic insights, this review aims to further improve early diagnosis and offer an updated perspective on current management strategies for the diverse range of complications associated with acute myocardial infarction.

Keywords