Journal of Advanced Pharmaceutical Technology & Research (Jan 2023)

Flavonoic content and antibacterial evaluation of Moringa oleifera Lam. leaves grow in Algeria

  • Sarah Boumaza-Hamladji,
  • Narimen Benhabyles,
  • Souheyla Toubal,
  • Djillali El Haddad,
  • Ouahiba Bouchenak,
  • Nerdjes Bellalemi,
  • Drifa Berrichi,
  • Ibtissem Meziani

DOI
https://doi.org/10.4103/JAPTR.JAPTR_126_23
Journal volume & issue
Vol. 14, no. 3
pp. 191 – 195

Abstract

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The objective of this study is to fight against antibiotic resistance, especially in urinary tract infection. To limit the spread of this scourge, we have proposed the use of flavonoid extract of the medicinal plant Moringa oleifera Lam against pathogenic bacteria of urinary tract infections. M. oleifera, was introduced in the arid regions of the Algerian Sahara for sustainable rural development in Algeria. The phytochemical study, revealed the presence of a multitude of metabolites. The yield of aqueous extract is 27.35% ± 1.95 and flavonoid concentration is 38.59 ± 0.002 mg EQ/gE. The high-performance liquid chromatography revealed the presence of 47 compounds, the most important of which are ascorbic acid (16.82%) and luteolin-7-Glycoside (26.8%). The aqueous extract has very significant antibacterial activity with an inhibition zone varying between 26.2 ± 0.25 (mm) for Bacillus anthracis and 12.66 ± 1.15 for Salmonella enteritidis.

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