Frontiers in Neurology (Jan 2022)
Olfactory Dysfunction in Patients With Coronavirus Disease 2019: A Review
- Guoli Wei,
- Guoli Wei,
- Guoli Wei,
- Guoli Wei,
- Jialin Gu,
- Jialin Gu,
- Jialin Gu,
- Zhancheng Gu,
- Zhancheng Gu,
- Zhancheng Gu,
- Cheng Du,
- Xiaofei Huang,
- Xiaofei Huang,
- Xiaofei Huang,
- Haiyan Xing,
- Haiyan Xing,
- Lingchang Li,
- Lingchang Li,
- Aiping Zhang,
- Aiping Zhang,
- Xingxing Hu,
- Xingxing Hu,
- Xingxing Hu,
- Xingxing Hu,
- Jiege Huo,
- Jiege Huo
Affiliations
- Guoli Wei
- Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- Guoli Wei
- Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
- Guoli Wei
- Nanjing Lishui District Hospital of Traditional Chinese Medicine, Nanjing, China
- Guoli Wei
- Department of Oncology, Yangzhou University Medical College, Yangzhou, China
- Jialin Gu
- Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- Jialin Gu
- Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
- Jialin Gu
- The Third Medical College, Nanjing University of Chinese Medicine, Nanjing, China
- Zhancheng Gu
- Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- Zhancheng Gu
- Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
- Zhancheng Gu
- The Third Medical College, Nanjing University of Chinese Medicine, Nanjing, China
- Cheng Du
- Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China
- Xiaofei Huang
- Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- Xiaofei Huang
- Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
- Xiaofei Huang
- The Third Medical College, Nanjing University of Chinese Medicine, Nanjing, China
- Haiyan Xing
- Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- Haiyan Xing
- Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
- Lingchang Li
- Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- Lingchang Li
- Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
- Aiping Zhang
- Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- Aiping Zhang
- Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
- Xingxing Hu
- Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- Xingxing Hu
- Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
- Xingxing Hu
- Nanjing Lishui District Hospital of Traditional Chinese Medicine, Nanjing, China
- Xingxing Hu
- Department of Oncology, Yangzhou University Medical College, Yangzhou, China
- Jiege Huo
- Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- Jiege Huo
- Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
- DOI
- https://doi.org/10.3389/fneur.2021.783249
- Journal volume & issue
-
Vol. 12
Abstract
The coronavirus disease 2019 (COVID-19) pandemic is wreaking havoc on public-health and economic systems worldwide. Among the several neurological symptoms of patients with COVID-19 reported in clinical practice, olfactory dysfunction (OD) is the most common. OD occurs as the earliest or the only clinical manifestation in some patients. Increasing research attention has focused on OD, which is listed as one of the main diagnostic symptoms of severe acute respiratory syndrome-coronavirus-2 infection. Multiple clinical and basic-science studies on COVID-19-induced OD are underway to clarify the underlying mechanism of action. In this review, we summarize the clinical characteristics, mechanisms, evaluation methods, prognosis, and treatment options of COVID-19-induced OD. In this way, we hope to improve the understanding of COVID-19-induced OD to aid early identification and precise intervention.
Keywords
