Nature Communications (Apr 2021)

FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division

  • Kevin D. Whitley,
  • Calum Jukes,
  • Nicholas Tregidgo,
  • Eleni Karinou,
  • Pedro Almada,
  • Yann Cesbron,
  • Ricardo Henriques,
  • Cees Dekker,
  • Séamus Holden

DOI
https://doi.org/10.1038/s41467-021-22526-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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Bacterial cell division by cell wall synthesis proteins is guided by treadmilling filaments of the cytoskeleton protein FtsZ. Here authors use nanofabrication, advanced microscopy, and microfluidics to resolve the function of FtsZ treadmilling in the Gram-positive model organism Bacillus subtilis.