Vascular Health and Risk Management (Jan 2024)
Sildenafil Use and Cigarette Smoking Associated with Intracerebral Hemorrhage: A Rare Case Report
Abstract
Mohamed Abdulahi Hassan,1,2 Ibrahim Abdullahi Mohamed,1 Abdullahi Abdirahman Omar,1 Zakaria Mohamed Adan,1 Bashiru Garba,3 Omar Hassan Badawi4 1Department of Internal Medicine and Intensive Care Unit, Dr. Sumait Hospitals Affiliated of SIMAD University, Mogadishu, Somalia; 2Department of Medicine and Surgery of Faculty of Medicine and Health Sciences, SIMAD University, Mogadishu, Somalia; 3Department of Public Health, Faculty of Medicine and Health Sciences, SIMAD University, Mogadishu, Somalia; 4Department of Radiology, Dr. Sumait Hospitals affiliated of SIMAD University, Mogadishu, SomaliaCorrespondence: Mohamed Abdulahi Hassan, Tel +252615987780, Email [email protected]: Intracerebral hemorrhage (ICH) is a serious condition characterized by bleeding within the brain tissue. Although the use of sildenafil, a vasodilator agent for erectile dysfunction, has been associated with rare cases of ICH, the combination of sildenafil usage and smoking as risk factors for ICH has not yet been reported. This case report describes the occurrence of ICH in a patient with a history of both sildenafil usage and heavy smoking.Case Presentation: A 53-year-old male, with a history of smoking and regular sildenafil use, was brought to the emergency department due to loss of consciousness with right-side weakness, he initially experienced with nausea, vomiting and dizziness after taking sildenafil 100mg tablet once. The Glasgow Coma Score (GCS) was 10 with side hemiparesis. Non-contrast CT revealed left thalamic acute hemorrhage with ventricular extension. Furthermore, a head CT angiography ruled out any vascular anomalies after that the patient was admitted to the intensive care unit (ICU) for conservative management. After three days on clinical and neurological improvement, the patient was transferred to the inpatient ward for further management, monitoring and physiotherapy. On day 6, the patient was discharged and planned for flow up.Conclusion: This rare case highlights the need for further research and awareness regarding the potential risks associated with the combination of sildenafil and heavy smoking. Healthcare professionals should carefully evaluate the individual risk factors of patients, educate them about potential complications, and consider alternative treatments if necessary. Additionally, patients should be encouraged to quit smoking and adopt a healthy lifestyle to minimize the risk of cerebrovascular events.Keywords: sildenafil, cigarette smoking, stroke, intracerebral hemorrhage
