Počki (Mar 2023)

COVID-19 as a cause of acute kidney transplant rejection: clinical and morphological analysis of a fatal case report

  • V.M. Demchenko,
  • M.S. Myroshnychenko,
  • M.M. Tsymbal,
  • V.L. Lysachenko,
  • O.O. Dyadyk,
  • M.O. Zhelieznikova

DOI
https://doi.org/10.22141/2307-1257.12.1.2023.395
Journal volume & issue
Vol. 12, no. 1
pp. 50 – 53

Abstract

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COVID-19 against the background of the respiratory system damage often causes changes in the morpho-functional state of the kidneys, accelerates the progression and development of complications of chronic kidney disease, and is the cause of a high mortality rate in kidney transplant recipients. In the article, the authors conduct a detailed clinical and morphological analysis of a fatal case report of acute kidney transplant rejection of antibody-mediated and cell-mediated genesis, the development of which was determined by the presence of COVID-19 in the patient. The authors emphasize that the morphological study is crucial for the diagnosis of renal transplant rejection. This clinical and morphological analysis of a case report shows the need for an individual approach to this category of patients for the purpose of timely diagnosis, treatment and prevention of COVID-19.

Keywords