USE OF VIBRIO CHOLERAE SURFACE STRUCTURES FOR SPECIFIC PROPHYLAXIS AND DIAGNOSTICS OF CHOLERA

Abstract

The need for efficient and cost-effective cholera vaccine hasn’t lost its actuality in view of the emergence of new strains leading to severe clinical forms of cholera and capable to replace strains of the seventh cholera pandemic, and in connection with the threat of cholera spreading beyond the borders of endemic countries. In this review data from literature sources are presented about the use of outer membrane proteins, vesicles, cell ghosts of the cholera causative agent in specific prophylaxis and diagnostics of the disease.

Keywords

• «тени» возбудителя холеры
• outer membrane proteins
• vesicles
• cell ghosts of cholera causative agent
• vaccine