Beilstein Journal of Organic Chemistry (Nov 2018)
Olefin metathesis catalysts embedded in β-barrel proteins: creating artificial metalloproteins for olefin metathesis
Abstract
This review summarizes the recent progress of Grubbs–Hoveyda (GH) type olefin metathesis catalysts incorporated into the robust fold of β-barrel proteins. Anchoring strategies are discussed and challenges and opportunities in this emerging field are shown from simple small-molecule transformations over ring-opening metathesis polymerizations to in vivo olefin metathesis.
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