Рациональная фармакотерапия в кардиологии (Jan 2016)

EFFICACY OF THERAPY WITH INDIRECT ANTICOAGULANTS: ROLE OF THE FOODSTUFF VITAMIN K CONTENTS

  • A. P. Momot,
  • O. V. Bespalova,
  • E. N. Vorobyova

DOI
https://doi.org/10.20996/1819-6446-2006-2-3-51-55
Journal volume & issue
Vol. 2, no. 3
pp. 51 – 55

Abstract

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The anticoagulants of indirect action during many years serve drugs of basic prophylaxis and therapy of thromboembolic episodes at cardiovascular , neurological, oncology, orthopaedic and other diseases, after surgical interventions and traumas, and also large bunch of the generically caused and acquired (secondary) thrombophilie. The contents of vitamin К1 in nutrition depend on a method of product preparation. The highest concentrations are found in dark green vegetables and grass: parsley, spinach, green turnip, and also in cabbage and lettuce. For achievement stable hypocoagulation at assignment of anticoagulants of indirect action the daily entering with nutrition of constant amounts of vitamin K (at a level 65-80 mkg/day) is necessary. Thus, a doctor at assignment of anticoagulants, is obliged to pay attention to character of a food and to inform patient about possible undesirable consequences at the use of products keeping high levels of vitamin К1.

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