Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals

Kobal Borut; Noventa Marco; Cvjeticanin Branko; Barbic Matija; Meglic Leon; Herzog Marusa; Bordi Giulia; Vitagliano Amerigo; Saccardi Carlo; Skof Erik

doi:10.2478/raon-2018-0030

Radiology and Oncology (Sep 2018)

Primary debulking surgery versus primary neoadjuvant chemotherapy for high grade advanced stage ovarian cancer: comparison of survivals

Kobal Borut,
Noventa Marco,
Cvjeticanin Branko,
Barbic Matija,
Meglic Leon,
Herzog Marusa,
Bordi Giulia,
Vitagliano Amerigo,
Saccardi Carlo,
Skof Erik

Affiliations

Kobal Borut: Division of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, Slovenia
Noventa Marco: Department of Woman and Child Health, University of Padua, Padua, Italy
Cvjeticanin Branko: Division of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, Slovenia
Barbic Matija: Division of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, Slovenia
Meglic Leon: Division of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, Slovenia
Herzog Marusa: Division of Gynaecology and Obstetrics, University Medical Centre Ljubljana, Ljubljana, Slovenia
Bordi Giulia: Department of Gynecology and Obstetrics, University of Insubria, Varese, Italy
Vitagliano Amerigo: Department of Woman and Child Health, University of Padua, Padua, Italy
Saccardi Carlo: Department of Woman and Child Health, University of Padua, Padua, Italy
Skof Erik: Department of Medical Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia

DOI: https://doi.org/10.2478/raon-2018-0030
Journal volume & issue: Vol. 52, no. 3
pp. 307 – 319

Abstract

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The aim of the study was to analyze the overall survival (OS) and progression free survival (PFS) of patients with high grade and advanced stage epithelial ovarian cancer (EOC) with at least 60 months of follow-up treated in a single gynecologic oncology institute. We compared primary debulking surgery (PDS) versus neoadjuvant chemotherapy plus interval debulking surgery (NACT + IDS) stratifying data based on residual disease with the intent to identify the rationale for therapeutic option decision and the role of laparoscopic evaluation of resectability for that intention.

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

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Abstract

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