Sphingosine 1-Phosphate- and C-C Chemokine Receptor 2-Dependent Activation of CD4+ Plasmacytoid Dendritic Cells in the Bone Marrow Contributes to Signs of Sepsis-Induced Immunosuppression

• Anna Smirnov,
• Stephanie Pohlmann,
• Melanie Nehring,
• Shafaqat Ali,
• Shafaqat Ali,
• Ritu Mann-Nüttel,
• Stefanie Scheu,
• Anne-Charlotte Antoni,
• Wiebke Hansen,
• Manuela Büettner,
• Miriam J. Gardiasch,
• Astrid M. Westendorf,
• Florian Wirsdörfer,
• Eva Pastille,
• Marcel Dudda,
• Stefanie B. Flohé

Affiliations

Anna Smirnov

Department of Orthopedics and Trauma Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Stephanie Pohlmann

Department of Orthopedics and Trauma Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Melanie Nehring

Department of Orthopedics and Trauma Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Shafaqat Ali

Institute of Medical Microbiology and Hospital Hygiene, University of Düsseldorf, Düsseldorf, Germany

Shafaqat Ali

Cells in Motion, Cluster of Excellence, University of Münster, Münster, Germany

Ritu Mann-Nüttel

Institute of Medical Microbiology and Hospital Hygiene, University of Düsseldorf, Düsseldorf, Germany

Stefanie Scheu

Institute of Medical Microbiology and Hospital Hygiene, University of Düsseldorf, Düsseldorf, Germany

Anne-Charlotte Antoni

Department of Orthopedics and Trauma Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Wiebke Hansen

Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Manuela Büettner

Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany

Miriam J. Gardiasch

Department of Orthopedics and Trauma Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Astrid M. Westendorf

Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Florian Wirsdörfer

Medical Faculty, Institute of Cell Biology (Cancer Research), University of Duisburg-Essen, Essen, Germany

Eva Pastille

Institute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Marcel Dudda

Department of Orthopedics and Trauma Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

Stefanie B. Flohé

Department of Orthopedics and Trauma Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany