Pulmonary mucosa-associated lymphoid tissue lymphoma forming a reversed halo sign from ground-glass opacity

Ayano Watanabe, MD; Koji Chihara, MD, PhD; Masato Fujii, MD, PhD; Kyoko Hijiya, MD, PhD; Kazuya Iwai, MD, PhD; Yuki Egawa, MD; Yoshitaka Abe, MD

Radiology Case Reports (Apr 2023)

Pulmonary mucosa-associated lymphoid tissue lymphoma forming a reversed halo sign from ground-glass opacity

Ayano Watanabe, MD,
Koji Chihara, MD, PhD,
Masato Fujii, MD, PhD,
Kyoko Hijiya, MD, PhD,
Kazuya Iwai, MD, PhD,
Yuki Egawa, MD,
Yoshitaka Abe, MD

Affiliations

Ayano Watanabe, MD: Department of Respiratory Medicine, Shizuoka City Shizuoka Hospital, 10-93, Ohte-machi, Aoi-ku, Shizuoka City, Shizuoka 420-8630, Japan; Corresponding author.
Koji Chihara, MD, PhD: Department of Thoracic Surgery, Shizuoka City Shizuoka Hospital, Shizuoka, Japan
Masato Fujii, MD, PhD: Department of Respiratory Medicine, Shizuoka City Shizuoka Hospital, 10-93, Ohte-machi, Aoi-ku, Shizuoka City, Shizuoka 420-8630, Japan
Kyoko Hijiya, MD, PhD: Department of Thoracic Surgery, Shizuoka City Shizuoka Hospital, Shizuoka, Japan
Kazuya Iwai, MD, PhD: Department of Hematology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan
Yuki Egawa, MD: Department of Pathology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan
Yoshitaka Abe, MD: Department of Diagnostic Radiology, Shizuoka City Shizuoka Hospital, Shizuoka, Japan

Journal volume & issue: Vol. 18, no. 4
pp. 1633 – 1636

Abstract

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The reversed halo sign (RHS) has been associated with various pulmonary diseases. We report a rare case of pulmonary mucosa-associated lymphoid tissue lymphoma forming a RHS from a ground-glass opacity (GGO). A 73-year-old man was followed-up for the GGO on his computed tomography images, which gradually extended peripherally. During the fourth year of follow-up, the GGO significantly evolved into a well-demarcated, oval lesion, with interlobular and intralobular septal thickenings, and multiple air spaces were surrounded by a well-defined thin consolidative rim, called the RHS. A pathologic study of the specimen via transbronchoscopic biopsy revealed pulmonary mucosa-associated lymphoid tissue lymphoma.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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