THE INFLUENCE OF DIABETES MELLITUS ON THE COURSE AND OUTCOMES OF MYOCARDIAL INFARCTION IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTIONS

Abstract

Aim. To study the clinical course and outcomes of myocardial infarction (MI) in diabetes mellitus patients (DM) and non-diabetic, underwent percutaneous coronary intervention (PCI).Material and methods. Totally, 99 MI patients included, that underwent PCI with stenting. Patients were selected to 2 groups by absence or presence of DM: group 1 (n=49) — DM type 2; group 2 (n=50) — non-diabetic and glucose intolerance. We studied the baseline clinical and demographic, as laboratory and instrumental characteristics of patients, specifics of in-patient stage of treatment and outcomes in 1 year after discharge.Results. There was predominance of women in DM2 group and developing MI. It was found, that DM patients adhered the preclinical treatment of ischemic heart disease in 47% cases and about 20% DM patients did not take glucose lowering medications. In patients from group 1 the arterial hypertension was diagnosed significantly more commonly in comparatively lower values of the left ventricle ejection fraction. More commonly than the other complication of MI, the acute heart failure developed (14%). By the end of the 1 year, DM patients nonsignificantly more commonly had recurrent hospitalizations for all cardiovascular causes, as the cases with fatal outcomes.Conclusion. The course of MI in DM has its specifics as comparatively lower values of myocardium contractility, significant lesion of coronary vessels, high number of acute period of MI complications with indefinite influence on the one-year prognosis.

Keywords

• myocardial infarction
• diabetes mellitus
• percutaneous coronary interventions
• prognosis