P460: ERK1/2 INHIBITION OVERCOMES RESSITANCE TO BCL2 INHIBITION IN ACUTE MYELOID LEUKEMIA BY IMPACT ON MITOCHONDRIAL DYNAMICS AND FUNCTION

• Priyanka Sharma,
• Sujan Piya,
• Natalia Baran,
• Anna Zal,
• Qi Zhang,
• Joanne Munck,
• Kim-Hien Dao,
• Martin Sims,
• Michael Andreeff,
• Gautam Borthakur

Affiliations

Priyanka Sharma

1 The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, United States

Sujan Piya

1 The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, United States

Natalia Baran

1 The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, United States

Anna Zal

1 The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, United States

Qi Zhang

1 The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, United States

Joanne Munck

3 Astex Pharmaceuticals, Cambridge, United Kingdom

Kim-Hien Dao

4 Astex Pharmaceuticals, Inc, Pleasanton, United States

Martin Sims

3 Astex Pharmaceuticals, Cambridge, United Kingdom

Michael Andreeff

1 The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, United States

Gautam Borthakur

1 The University of Texas MD Anderson Cancer Center, Department of Leukemia, Houston, United States