RETRACTED: Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).This article has been retracted at the request of the authors.The authors became aware of an issue with incorrect loading control images being presented and are now retracting the article in the interests of maintaining their publication standards and those of the journal. The authors maintain that these presentational errors do not impact the underlying scientific findings of the article, some of which have been verified in other laboratories.Figure 4 contains incorrect loading control images of SOD1G93A mouse. The b-actin images blots presented are SOD1G93A rat b-actin bands that were accidentally used when compiling the image for publication. Similarly, in Figure 1 the samples were run in two separate experiments with the controls split across the two blots. The b-actin for one set of controls was accidentally used for the second controls. The authors state that quantifications were performed using the correct b-actin bands.In figure 1, concerns were raised that each of the panels had 13 lanes except for the ATF panel which appeared to have only twelve lanes. The authors state that the ATF6 panel has 13 lanes, but last two control lanes of the gel have no signal, making it difficult to accurately align the end part of the gel correctly for display in the figure.