Biomolecules (Sep 2019)
Antidiabetic Potential of Medicinal Plants and Their Active Components
- Bahare Salehi,
- Athar Ata,
- Nanjangud V. Anil Kumar,
- Farukh Sharopov,
- Karina Ramírez-Alarcón,
- Ana Ruiz-Ortega,
- Seyed Abdulmajid Ayatollahi,
- Patrick Valere Tsouh Fokou,
- Farzad Kobarfard,
- Zainul Amiruddin Zakaria,
- Marcello Iriti,
- Yasaman Taheri,
- Miquel Martorell,
- Antoni Sureda,
- William N. Setzer,
- Alessandra Durazzo,
- Massimo Lucarini,
- Antonello Santini,
- Raffaele Capasso,
- Elise Adrian Ostrander,
- Atta -ur-Rahman,
- Muhammad Iqbal Choudhary,
- William C. Cho,
- Javad Sharifi-Rad
Affiliations
- Bahare Salehi
- Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran
- Athar Ata
- Department of Chemistry, Richardson College for the Environmental Science Complex, The University of Winnipeg, Winnipeg, MB R3B 2G3, Canada
- Nanjangud V. Anil Kumar
- Department of Chemistry, Manipal Institute of Technology, Manipal University, Manipal 576104, India
- Farukh Sharopov
- Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, Dushanbe 734003, Tajikistan
- Karina Ramírez-Alarcón
- Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepción 4070386, Chile
- Ana Ruiz-Ortega
- Facultad de Educación y Ciencias Sociales, Universidad Andrés Bello, Autopista Concepción—Talcahuano, Concepción 7100, Chile
- Seyed Abdulmajid Ayatollahi
- Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, Iran
- Patrick Valere Tsouh Fokou
- Department of Biochemistry, Faculty of Science, University of Yaounde 1, Yaounde P.O. Box 812, Cameroon
- Farzad Kobarfard
- Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, Iran
- Zainul Amiruddin Zakaria
- Laboratory of Halal Science Research, Halal Products Research Institute, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
- Marcello Iriti
- Department of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, 20133 Milan, Italy
- Yasaman Taheri
- Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, Iran
- Miquel Martorell
- Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepción 4070386, Chile
- Antoni Sureda
- Research Group on Community Nutrition and Oxidative Stress, Laboratory of Physical Activity Sciences, and CIBEROBN—Physiopathology of Obesity and Nutrition, CB12/03/30038, University of Balearic Islands, E-07122 Palma de Mallorca, Spain
- William N. Setzer
- Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA
- Alessandra Durazzo
- CREA—Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy
- Massimo Lucarini
- CREA—Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy
- Antonello Santini
- Department of Pharmacy, University of Napoli Federico II, Via D. Montesano, 49-80131 Napoli, Italy
- Raffaele Capasso
- Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy
- Elise Adrian Ostrander
- Medical Illustration, Kendall College of Art and Design, Ferris State University, Grand Rapids, MI 49503, USA
- Atta -ur-Rahman
- H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
- Muhammad Iqbal Choudhary
- H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
- William C. Cho
- Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong, China
- Javad Sharifi-Rad
- Department of Pharmacology, Faculty of Medicine, Jiroft University of Medical Sciences, Jiroft 7861756447, Iran
- DOI
- https://doi.org/10.3390/biom9100551
- Journal volume & issue
-
Vol. 9,
no. 10
p. 551
Abstract
Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood sugar imposes serious consequences for health. Conventional antidiabetic drugs are effective, however, also with unavoidable side effects. On the other hand, medicinal plants may act as an alternative source of antidiabetic agents. Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies. The beneficial potential of each plant matrix is given by the combined and concerted action of their profile of biologically active compounds.
Keywords
