Indian Journal of Ophthalmology (Jan 2020)

Role of secukinumab in ankylosing spondylitis with tubercular uveitis

  • Padmamalini Mahendradas,
  • Vikramraj K Jain,
  • Sherina Thomas,
  • Ankush Kawali,
  • Srinivasan Sanjay,
  • Bhujang K Shetty

DOI
https://doi.org/10.4103/ijo.IJO_1081_20
Journal volume & issue
Vol. 68, no. 11
pp. 2569 – 2572

Abstract

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We present the case of a 32-year-old Indian male one-eyed individual with a history of unilateral panuveitis with HLA B 27 positive spondyloarthropathy on systemic immunosuppressant (Adalimumab). He developed recurrent inflammation in the same eye in a span of 2 years, later complicated with retinal vasculitis. On evaluation, he was diagnosed with tubercular uveitis and started on antitubercular treatment along with systemic steroids. Inview of Increased IOP due to steroid response, Inj. Secukinumab ( IL 17 A inhibitor) was started and significant improvement was noted.

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