Exploiting Substrate Specificities of 6‑O‑Sulfotransferases to Enzymatically Synthesize Keratan Sulfate Oligosaccharides

• Yunfei Wu,
• Gaël M. Vos,
• Chin Huang,
• Digantkumar Chapla,
• Anne L. M. Kimpel,
• Kelley W. Moremen,
• Robert P. de Vries,
• Geert-Jan Boons

Affiliations

Yunfei Wu

Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands

Gaël M. Vos

Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands

Chin Huang

Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, United States

Digantkumar Chapla

Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, United States

Anne L. M. Kimpel

Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands

Kelley W. Moremen

Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, United States

Robert P. de Vries

Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands

Geert-Jan Boons

Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands