Biologically active preparations influence on levels of thiol groups in tissues and organs of pregnant rats Wistar at hypoxia stress in the pollution conditions

Abstract

It is studied the influence of biologically active additives namivit and a superprotamine on activity of antioxidatic protection system at pregnant rats Wistar at action of an acute hypobaric hypoxia. It is established that the namivit and superprotamine application strengthened antioxidatic protection and reduced influence of oxidative stress by an pregnant females organism. It is shown that introduction to rats investigated preparations substantially reduced the maintenance of the general and albuminous SH-groups, and also enlarged level of free glutathione SH-groups. Thus the namivit's antyhypoxia effect has been expressed in a larger measure, than a superprotamine.

Keywords

• hypoxia
• pregnancy
• thiol groups
• biologically active preparations