A single mode of population covariation associates brain networks structure and behavior and predicts individual subjects’ age

Abstract

Brent McPherson and Franco Pestilli build on a large-scale data set from the Cambridge Centre for Aging Neuroscience to examine multivariate relationships between structural brain networks, behavior, and aging in healthy patients aged 18-88 years. They find that the age of individual subjects is predicted by the association between structural connectivity and behavioral measures. They provide a reproducible data processing pipeline at brainlife.io that can be applied to other datasets.