Hereditary Cancer in Clinical Practice (Nov 2004)
In the Beginning There Was Colectomy: Current Surgical Options in Familial Adenomatous Polyposis
Abstract
Abstract Multiple colonic polyps, almost guaranteed colorectal cancer by the age of forty-five and an increased risk of non-colonic cancers characterise the autosomal dominant condition Familial Adenomatous Polyposis (FAP) 1. The patients and families faced with such a diagnosis present many difficult management challenges, both surgical and non-surgical. We discuss the current surgical options for treatment of the more significant manifestations of FAP arising in the colorectum and duodenum as well as desmoid disease
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