Folia Histochemica et Cytobiologica (Apr 2010)
Inhibition of cysteine peptidase activity in ascitic fluid in pancreatic cancer patients
Abstract
The work's objective is to answer the question whether there is any possibility of activity inhibition of cysteinepeptidases inhibitors playing an important role in key processes accompanying cancer formation, including pancreas. Thereis a justified speculation that specific inhibitors of these enzymes may inhibit development of cancer processes by inhibitingtheir activity. In vitro studies confirmed that these enzymes in ascitic fluid were inhibited with egg whites inhibitors evento 90% of their original activity.