International Journal of Nanomedicine (Sep 2019)
Pyridine azo disperse dye derivatives and their selenium nanoparticles (SeNPs): synthesis, fastness properties, and antimicrobial evaluations
Abstract
Huda SA Alnassar,1 Maher HE Helal,2 Ahmed A Askar,3 Doaa M Masoud,2 Amira EM Abdallah2 1Department of Laboratories Technology, College of Technological Studies, Public Authority for Applied Education and Training, Fayha 70654, Kuwait; 2Department of Chemistry, Faculty of Science, Helwan University, Cairo 11795, Egypt; 3Departments of Botany and Microbiology, Faculty of Science (Boys), Al-Azhar University, Cairo 11751, EgyptCorrespondence: Amira EM AbdallahDepartment of Chemistry, Faculty of Science, Helwan University, Ain Helwan, Cairo 11795, EgyptTel +20 109 176 9838Email [email protected]: Aiming to produce pyridine azo disperse dyes with good fastness properties and promising antimicrobial activity, a number of novel systems of polyfunctionalized pyridine azo dyes and their selenium nanoparticles (SeNPs) were synthesized.Materials and methods: The synthesized products were formed by the reaction of diazotized aniline derivatives or diazotized amino antipyrene with any of dibenzoyl methane or benzoyl acetone and cyanoacetamide in boiling ethanolic sodium ethoxide. The structures of the newly synthesized compounds were elucidated by elemental analysis and spectral data. Moreover, (SeNPs) of the pyridine azo disperse dyes were characterized by Ultra-Violet -Visible spectrophotometry, dynamic light scattering , X-ray diffraction, and transmission electron microscope analysis. On the other hand, the synthesized dyes and its (SeNPs) were applied for disperse dyeing of nylon 66 and their fastness properties were measured, such as washing, rubbing, perspiration, and light fastness. In addition, the antimicrobial activities for all the synthesized compounds and for (SeNPs) prepared compounds (2bN, 2cN, 2fN, 2gN, 2hN) were evaluated.Results: Compounds 2bN, 2c, 2cN, 2fN, 2gN, 2h, 2hN, and 2i were the most active compounds against all Gram-positive and Gram-negative bacterial species. While, compounds 2b, 2f, 2g, and 5b were the most active toward some of the bacterial strains (at least two from the selected four strains). Moreover, compounds 2bN, 2cN, 2fN, 2gN, 2h, 2hN showed higher activity toward the fungal strain. Also, the minimal inhibitory concentrations for all the most active compounds were determined.Conclusion: Finally, all the (SeNPs) compounds revealed higher activity against bacterial and fungal strains than the other synthesized compounds.Keywords: pyridine azo dyes, (SeNPs) azo dye, fastness properties, dyeing, antimicrobial, minimal inhibitory concentrations (MIC)
