Vitamin D3 deficiency and its role in the development of metabolic disorders

Abstract

Data are presented on the effect of vitamin D3 on calcium-phosphorus and carbohydrate metabolism, as well as on the functional activity of pancreatic β cells against the background of hypovitaminosis D and in experimental diabetes in mice. Some mechanisms of disturbance of vitamin D3 metabolism and the results of its clinical use in patients with type 1 and type 2 diabetes mellitus are described.

Keywords

• hypovitaminosis D
• carbohydrate metabolism
• experimental diabetes
• D deficiency in type 1 and type 2 diabetes mellitus