Spatiotemporal organisation of protein processing in the kidney

Marcello Polesel; Monika Kaminska; Dominik Haenni; Milica Bugarski; Claus Schuh; Nevena Jankovic; Andres Kaech; Jose M. Mateos; Marine Berquez; Andrew M. Hall

doi:10.1038/s41467-022-33469-5

Nature Communications (Sep 2022)

Spatiotemporal organisation of protein processing in the kidney

Marcello Polesel,
Monika Kaminska,
Dominik Haenni,
Milica Bugarski,
Claus Schuh,
Nevena Jankovic,
Andres Kaech,
Jose M. Mateos,
Marine Berquez,
Andrew M. Hall

Affiliations

Marcello Polesel: Institute of Anatomy, University of Zurich
Monika Kaminska: Institute of Anatomy, University of Zurich
Dominik Haenni: Center for Microscopy and Image Analysis, University of Zurich
Milica Bugarski: Institute of Anatomy, University of Zurich
Claus Schuh: Institute of Anatomy, University of Zurich
Nevena Jankovic: Institute of Anatomy, University of Zurich
Andres Kaech: Center for Microscopy and Image Analysis, University of Zurich
Jose M. Mateos: Center for Microscopy and Image Analysis, University of Zurich
Marine Berquez: Institute of Physiology, University of Zurich
Andrew M. Hall: Institute of Anatomy, University of Zurich

DOI: https://doi.org/10.1038/s41467-022-33469-5
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 13

Abstract

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Polesel et al. visualize plasma protein filtration, uptake and metabolism in the kidneys of living mice in real-time. They reveal coordinated activity of different specialized tubular segments, with major compensatory adaptations occurring in disease states.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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