Communications Medicine (Jan 2023)

Genetic analyses implicate complex links between adult testosterone levels and health and disease

  • Jaakko T. Leinonen,
  • Nina Mars,
  • Leevi E. Lehtonen,
  • Ari Ahola-Olli,
  • Sanni Ruotsalainen,
  • Terho Lehtimäki,
  • Mika Kähönen,
  • Olli Raitakari,
  • FinnGen Consortium,
  • Terhi Piltonen,
  • Mark Daly,
  • Tiinamaija Tuomi,
  • Samuli Ripatti,
  • Matti Pirinen,
  • Taru Tukiainen

DOI
https://doi.org/10.1038/s43856-022-00226-0
Journal volume & issue
Vol. 3, no. 1
pp. 1 – 15

Abstract

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Leinonen et al. investigate correlations between testosterone levels and disease using genetic and health registry data from the UK Biobank and FinnGen. There is a lack of evidence for normal variation in testosterone levels having a causal contribution to most non-sex-specific traits.