BOADICEA model: updates to the BRCA2 breast cancer risks for ages 60 years and older

Lorenzo Ficorella; Xin Yang; Douglas F. Easton; Antonis C. Antoniou

doi:10.1038/s44276-024-00079-1

BJC Reports (Jul 2024)

BOADICEA model: updates to the BRCA2 breast cancer risks for ages 60 years and older

Lorenzo Ficorella,
Xin Yang,
Douglas F. Easton,
Antonis C. Antoniou

Affiliations

Lorenzo Ficorella: Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
Xin Yang: Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
Douglas F. Easton: Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge
Antonis C. Antoniou: Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge

DOI: https://doi.org/10.1038/s44276-024-00079-1
Journal volume & issue: Vol. 2, no. 1
pp. 1 – 3

Abstract

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Abstract Breast cancer risks in older BRCA2 pathogenic variant carriers are understudied. Recent studies show a marked decline in the relative risk at older ages. We used data from two large studies to update the breast cancer risks in the BOADICEA model for BRCA2 carriers 60 years and older.

Published in BJC Reports

ISSN: 2731-9377 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.nature.com/bjcreports/

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