Open Medicine (Feb 2019)

Oncoprotein LAMTOR5 activates GLUT1 via upregulating NF-κB in liver cancer

  • Zhou Jing,
  • Li Yajun,
  • Li Danhua,
  • Liu Zhi,
  • Zhang Jie

DOI
https://doi.org/10.1515/med-2019-0022
Journal volume & issue
Vol. 14, no. 1
pp. 264 – 270

Abstract

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Accumulating reports reveal that serving as an oncogenic factor LAMTOR5 is involved in the progression of many specific cancers. Glucose transporter 1 (GLUT1) is frequently identified in many cancers. However, it remains unexplored whether GLUT1 plays a role in LAMTOR5-enhanced liver cancer. Here, we aim to decipher the function of LAMTOR5 in the regulation of GLUT1 in liver cancer.

Keywords