Kidney damage in some rheumatic diseases

Abstract

Rheumatic disease with visceral manifestations pose a potential problem for the disease course and its prognosis. Such visceral manifestations may include kidney damage or complications, particularly in certain cases bone, joint and muscular manifestations of rheumatic disease. Glomerular immune inflammatory diseases appear in cases where the rheumatic disease progresses to the point of becoming a systemic inflammatory process; AA-amyloidosis appears in cases of prolonged active articular process; while tubulo-interstitial lesion occurs during the treatment with non-steroidal anti-inflammatory drugs and analgesics. Progressive nature of kidney failure in rheumatic diseases, leading to the development of terminal renal insufficiency, presents a problem for the affected individuals in terms of their ability to live in conditions of renal replacement therapy.

Keywords

• rheumatoid arthritis
• ankylosing spondylarthritis
• psoriatic arthritis
• AA-amyloidosis
• interstitial nephritis
• cytotoxic agents
• biological agents
• non-steroidal anti-inflammatory drugs