Enteroviruses Associated with Aseptic Meningitis in Poland, 2011–2014

Abstract

A 4-year study (2011–2014) of patients with meningitis was performed. Out of the 686 cerebrospinal fluid samples, 465 (67.8%) were posi­tive for eneteroviruses using RT-PCR and out of 334 clinical samples, 216 (64.7%) were positive for enteroviruses using cell culture methods. The highest detection rate was observed in the summer and autumn. In total, 185 enteroviruses were identified by using neutralization test. Echovirus 6 and 30 were the most common (41.7% and 37.5% respectively). The highest frequency of neurological infections (32.7%) occurred in children aged 5–9 years, mostly males (63.9%).

Keywords

• aseptic meningitis
• cerebrospinal fluid
• diagnostic PCR
• enteroviruses