Lipid peroxidation in the rat blood under the single alimentary incorporation of 90Sr + 90Y

Abstract

Lipid peroxidation (LP) following the single 90Sr + 90Y alimentary injection at the activity of 113,9 kBq per animal in the blood of Wistar adult mail rats by means of chemiluminescence was studied. Dynamics of LP changes was revealed to have the extreme features with minimum on the 1-st day and maximum on the 3-rd day. Since the 7-th day the meanings of cheminulescence indicators linear depend on the effective doze quantity, moreover for all the meanings (І1, І2 and S), besides the final intensity of luminescence (Ik), this dependence practically equals determination coefficient R2 = 0,987. For Ik the doze dependence is inversed to R2 = 0,918. Obtained data demonstrate that the radiation loading causes the initiation of antioxidant defence adaptation-compensatory mechanisms at the early period of radiation influence.