Royal Society Open Science (Jan 2018)

Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus

  • Shuihong Li,
  • Qianqian Mou,
  • Xinya Xu,
  • Shuhua Qi,
  • Polly H. M. Leung

DOI
https://doi.org/10.1098/rsos.172466
Journal volume & issue
Vol. 5, no. 5

Abstract

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Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections.

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