CHEMOTHERAPY CARDIOTOXICITY SCREENING WITH CARDIAC TROPONINS

Abstract

Recently, chemotherapy is one of the most trustworthy methods for treatment of malignant tumors and blood pathology. However clinical effect of the drugs not always matches with safety. These facts play as a solid evidence for the necessity of studying the problems related to side effects of the drugs, and, particularly, of cardiotoxicity, as reversible and/or irreversible damage of cardiomyocytes. Currently, the most sensitive ad specific markers of myocardium cells are troponins T and I. According with this, the main aims of this article are analysis of literary data for the problem of cardiac troponins application as cardiotoxicity revealing in oncology patients, and summon of more attention to this direction of science. The article provides a collection of the key points of all available studies at the moment, shows generalized analysis, analyses also the Russian and European Guidelines from the point of view related to troponins tests in oncology patients.

Keywords

• troponin
• cardiotoxicity
• chemotherapy