Armaghane Danesh Bimonthly Journal (Apr 2017)
The effect of Regular Aerobic Exercise Along with Vitamin C Consumption on Homocysteine levels and Insulin Resistance in Obese Girls
Abstract
ABSTRACT Background and aim: Childhood obesity is associated with an increased risk of cardiovascular complications and multiple metabolic such as insulin resistance and hyperhomocysteinemia. The aim of this study was to investigate the effect of regular aerobic exercise along with vitamin C consumption on the homocysteine levels and insulin resistance in obese girls. Methods: In the present semi-experimental study, 28 obese girls aged 8 to 12 years and body mass index 95% were selected and randomly divided as follow: control, exercise training, vitamin C and exercise training+ vitamin C (combined) groups. Aerobic exercise was consisted of exercise movements at 50% to 70% maximal heart rate and 3 sessions per week for 8 weeks. Vitamin C and combined groups consumed 500mg vitamin C tablets every other day. Fasting blood samples were collected before and 48 hour after the last intervention. For statistical analysis, One Way Analysis Variance (ANOVA), post hoc Tukey and independent t-test were used. Results: Eight weeks of aerobic exercise, vitamin C and the combined intervention were resulted a significant decrease in the levels of glucose, insulin, homocysteine and insulin resistance in obese girls (P<0.05). Furthermore each of three interventions was associated with a significant percent changes in these veraibles compared with control group. But the effect of combined intervention on the decrease in these variables were greater compared with other interventions (p<0.05). Conclusion: These findings suggested that both of aerobic exercise and vitamin C consumption non-drug can cause down regulation of homocysteine and insulin resistance levels in obese girls. Thus, the combined effect of regular aerobic exercise and vitamin C intervention is associated with the augmentation of these effects.
