Communications Biology (Jun 2021)

Bacterial load slopes represent biomarkers of tuberculosis therapy success, failure, and relapse

  • Gesham Magombedze,
  • Jotam G. Pasipanodya,
  • Tawanda Gumbo

DOI
https://doi.org/10.1038/s42003-021-02184-0
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 13

Abstract

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Magombedze et al. propose a new method combining mathematical modeling and machine learning to derive early (within 2 months) effective predictive biomarkers from bacterial load slopes for tuberculosis long term treatment outcomes, thereby accurately predicting treatment failure and success.