Examination of the influence of different adjuvants on the immunogenicity of vaccines against parainfluenza 3 virus in cattle

Abstract

The objective of our research was to examine the influence of different adjuvants on immunogenicity of vaccine against parainfluenza 3 virus in cattle. In the research there was used the commercial vaccine Respi-ol against PI3 virus in cattle, produced by VZS from Subotica as well as the experimental vaccine against the same virus prepared with completed adjuvant Emulsigen. The research was performed on two experimental groups of 12 calves each. The animals were immunized twice, in the interval of 21 days. The third group of 6 calves was a control. The results of the research showed that a smaller amount of adjuvent Emulsigen per vaccine dose provided a satisfactory height of titre of virus neu­tralizing antibodies in the blood serum samples of vaccinated calves in regard to prescribed greater amount of standard oil adjuvant contained in commercial Respi-ol vaccine.

Keywords

• parainfluenza 3 virus
• vaccine
• adjuvant Emulsigen