The case of hemoglobinopathy E

Abstract

Abnormal unstable hemoglobins are common in certain geographic areas (Hb S, Hb C, Hb E, Hb D). The clinical manifestations in carriers of abnormal hemoglobins may be absent or expressed in the form of severe hemolytic anemia with high mortality. The article describes the case with the combination of Hb E and erythrocytosis, which caused some difficulties in the diagnosis of disease.

Keywords

• hemoglobinopathies
• homozygous and heterozygous carriage
• Hb E (α2β2 26glu→liz)